728x90
Premature Births

Talking Terbutaline

Preterm Labor Drug Causes Controversy

Terbutaline and preterm laborWhen a mom-to-be is struck with preterm labor, all she and the father can think about is stopping it. Every day that full labor can be fought off is another day of development for their baby, and in this case, a single day means a lot.

The medications to stop preterm labor are varied, as are their results. Some generate a great deal of controversy on their safety and effectiveness. But perhaps no drug for preterm labor has generated more debate than terbutaline.

What Is Terbutaline?
Dr. Randy A. Fink, a board certified OB/GYN in private practice in Miami, Fla., as well as a Fellow of the American College of Obstetricians and Gynecologists, says that terbutaline is from a class of drugs known as beta-adrenergic receptor agonists. These drugs cause relaxation of smooth muscle, such as that of the uterus. The drug is approved by the FDA for treating asthma.

Terbutaline is from a class of drugs known as beta-adrenergic receptor agonists.

"When the uterus is contracting, such as during preterm labor, we would like to have a way to stop this activity – to relax the uterine muscles and stop the contractions," Dr. Fink says. "A similar medication known as ritodrine was approved by the Food and Drug Administration (FDA) in 1980 as a labor-inhibiting agent (known as a tocolytic), but the drug is no longer available on the market. Since terbutaline is so similar, it is frequently used for this purpose even though it is not FDA approved for labor inhibition."

Dr. Fink says it is important when looking at the effectiveness of any preterm labor drug to understand the difference between preterm labor and preterm contractions. The uterus is a muscle that is built to do one thing: contract. Many pregnant women have crampy preterm uterine contractions that cause them to present to labor and delivery units for evaluation and treatment. Terbutaline is often given in the form of a subcutaneous injection to stop these annoying uterine contractions. Terbutaline can also be given in oral form (a pill) for pregnant women to take at home to stop contractions.


pages: 1 2 3 4
WHAT PEOPLE ARE SAYING ABOUT...
Post as:
Comment Text:
 
CAPTCHA:
Please note that any comments submitted become the property of Disney Family / iParenting and can be edited and posted at our discretion.
 
cancel
lcf says
4 days, 5 hours ago

I took terbutaline in 1992. I had preterm labor at 24 weeks gestation. I used the pump. My son was born at 31 weeks. He had a wonderful and normal childhood. He is 16 years old and has been recently diagnosed with Bipolar and general anxiety disorder. I am devastated. I do not know if my taking terbutaline has a connection with my son's illness.

Anonymous says
3 weeks, 5 days ago

I have 16 year old twins and i took terbutaline for 3 weeks they have a host of LD.BE CAREFUL taking it,did it cause the LD...I don't know.

Anonymous says
October 9, 2009

I am now 28 weeks - was given terbutaline at the hospital last week for pre-term contractions. The contractions eventually subsided after a few hours and 3 shots of terbutaline. I have continued to take the medication in pill form. Agree that it was making my heart race like crazy in the beginning, but now my body has gotten used to it (after a few days) - baby and everything checked out fine. Most importantly, the baby is staying in and healthy! :)

Anonymous says
September 14, 2009

i am 36 weeks pregnant and was given terbutaline at the hospital for pre-term labor. i was also given a prescription for an oral dose every 4 hours. this drug makes me feel horrible. my whole body shakes, i can't sleep and i have been having trouble breathing. i ama single mother and have a two yr old and a 10 month old. as if taking care of them 36 weeks pregnant wasn't hard enough this drug makes me terrified to hold my son. my muscles are weak and tired and i am so nauseated i cant eat anything. i really dont recommend using terbutaline unless it is absolutely needed.

portland mom says
August 11, 2009

i know that there is some scary information out there about terbutaline - i have read ALL of it, and much of it while i was on the drug and in the hospital for a month and a half with pre-term labor. at 30 weeks i was put on very restricted bedrest, with 5 contractions per hour and my cervix 75% effaced. my fetal fibronectin tests continually came back positive. i took terbutaline in pill form, every 4-6 hours, for a month and a half. i was scared and had very intellectual discussions with every doctor at my hospital about my concerns, and they all believed it would serve me best to stay on the drug. having had asthma in early childhood and a high tolerance for caffeine, i actually had few problems on the drug at all. the speedy feeling never interfered with my sleep, my well-being, my ability to stay in bed happily. additionally, the baby didn't seeme to have any side effects from it in the womb. i once insisted that i go off of it for a day to see what would happen, and the contractions started immediately and progressed so quickly and rapidly, that they immediately gave me a shot to slow them until i could go back on the drug. i know the concerns, i've searched EVERY article on the internet, and in the end, i have a beautiful, smart, happy, normal, fun, energetic little toddler and that's my proof that i did what was right for us.

Content provided on this site is for educational purposes only and should not be construed to be medical advice, diagnosis or treatment.
Click here for additional information.

Welcome, please join our community!
New guest? Sign up!   Returning guest? Sign in!
This content requires flash player 9. Click here to upgrade your flash player.
award winning baby nursery essentials
SOUND OFF! VOTE & DISCUSS

Michelle and Jim Bob Duggar were recently named Parents of the Year by a non-profit organization. Do you think they deserve this title?

  results
AWARD WINNING PRODUCTS
JOIN THE BOOK CLUB

Join the Pregnancy Today Book Club for some great reads. More >

GALLERIES

728x90