RhoGam is given to all Rh- (Rhesus negative) women between the 28th to 29th week of pregnancy if the father of the baby's blood contains the Rh+ (Rhesus positive) antigen. RhoGam is a protein that can bind to Rh+ fetal blood cells and prevent your immune system recognizing these fetal cells as foreign. Fetal blood cells commonly enter the blood stream of the mother. Without RhoGam, your body could try to destroy these Rh+ fetal cells -- your baby's blood. This could have serious impact on subsequent pregnancies, as the next baby could suffer from the effects stemming from bilirubin build-up (jaundice).

Prior to the introduction of RhoGam, about 10-15% of Rh- women became sensitized to the fetal blood cells, usually at the time of delivery. Less than 2% of those that became sensitized did so prior to delivery. It is highly unlikely there will be any problem related to this slight delay.

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